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OCT4 抗体 (AA 1-134)

The 小鼠 单克隆 anti-OCT4 antibody (Clone Oct4-3508) (ABIN7868119) specifically detects OCT4 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868119
发货至: 中国
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Quick Overview for OCT4 抗体 (AA 1-134) (ABIN7868119)

抗原

See all OCT4 (POU5F1) 抗体
OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This OCT4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

Oct4-3508
  • 抗原表位

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    AA 1-134

    原理

    Oct4 Antibody / POU5F1

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 1-134 was used as the immunogen for the Oct4. antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Oct4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the Oct4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

    别名

    Oct4

    背景

    Oct4 Transcription factor that binds to the octamer motif (5). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Interacts with UBE2I and ZSCAN10. Interacts with PKM2. Interacts with WWP2. Transcriptional activity is positively regulated by PKM2. Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. Belongs to the POU transcription factor family. Class- 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

    UniProt

    Q01860

    途径

    Stem Cell Maintenance
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