BATF3 抗体 (AA 1-123)
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北京 101111
Quick Overview for BATF3 抗体 (AA 1-123) (ABIN7868023)
抗原
See all BATF3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-123
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原理
- SNFT Antibody / BATF3
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-123) from the human protein was used as the immunogen for the SNFT antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the SNFT antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SNFT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BATF3 (Basic Leucine Zipper Transcriptional Factor ATF-Like 3 (BATF3))
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别名
- SNFT
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背景
- SNFT, also known as BATF3 (basic leucine zipper transcription factor, ATF-like 3), JUNDM1 or JDP1, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, SNFT functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. The gene encoding SNFT maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
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UniProt
- Q9NR55
抗原
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