CCL23 抗体 (AA 1-120)
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北京 101111
Quick Overview for CCL23 抗体 (AA 1-120) (ABIN7868017)
抗原
See all CCL23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-120
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原理
- CCL23 Antibody / MPIF-1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1-120) from the human protein was used as the immunogen for the CCL23 antibody.
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亚型
- IgG2, kappa
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anti-Chemokine (C-C Motif) Ligand 23 (CCL23) antibody
CCL23 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 1-137) antibodyCCL23 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 23 (CCL23) antibodyCCL23 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 1-137) antibodyCCL23 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 23 (CCL23) (C-Term) antibodyCCL23 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 22-120) antibodyCCL23 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CCL23 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Myeloid Progenitor Inhibitory Factor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
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别名
- CCL23
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背景
- Small inducible cytokine A23 precursor (CCL23), also called CK-b-8 and Myeloid Progenitor Inhibitory Factor 1 (MPIF-1), is a chemokine that binds to the receptor CCR1. It is involved in the immune response and inhibits production of polymorphonuclear leukocytes (PMNs) and monocytes in bone marrow. In addition, CCL23 has a splice variant, CK-b-8-1, and both variants chemoattract lymphocytes, monoctyes and neutrophils. CCL23 also promotes angiogenesis and endothelial cell migration via its actions on the CCR1 receptor. Proinflammatory proteases cleave an N-terminal domain of CCL23, improving the potency of its CCR1-mediated signaling up to 1000- fold in vitro. N-truncated CCL23 is found in high levels in synovial fluids of rheumatoid arthritis patients, suggesting a role of protease release during an inflammatory response. High levels of CCL23 mRNA expression occur in human fetal bone osteoblasts and chondrocytes, indicating a possible role for CCL23 in the recruitment of osteoclast precursors to the sites of bone reabsorption.
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UniProt
- P55773
抗原
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