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Recombinant TdT 抗体 (AA 1-100)

The 小鼠 单克隆 anti-TdT antibody is suitable to detect TdT in samples from 人. It has been validated for ELISA 和 IHC (p).
产品编号 ABIN7867839
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Recombinant TdT 抗体 (AA 1-100) (ABIN7867839)

抗原

See all TdT (DNTT) 抗体
TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

抗体类型

Recombinant Antibody

适用

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宿主

  • 89
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小鼠

克隆类型

  • 63
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  • 1
单克隆

标记

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This TdT antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RDNTT-6909
  • 抗原表位

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    AA 1-100

    原理

    DNTT Antibody / TdT / DNA Nucleotidylexotransferase (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 1-100 was used as the immunogen for the DNTT antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the DNTT antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the DNTT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

    别名

    DNTT

    背景

    Terminal deoxynucleotidyl transferase (TdT) is an unusual deoxynucleotide polymerizing enzyme with a molecular weight of about 58 kDa found normally only in B- and T-cell lymphoblasts/prelymphocytes. TdT generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Rare TdT-positive cells are regularly detected in thymus and bone marrow. Typically, TdT expression in the thymus is very variable from cell to cell since it is rapidly decreased in more mature T-cells. TdT-positive cells may occasionally be found in tonsils, lymph nodes and extranodal lymphoid tissue. Immunohistochemical detection of TdT has value in classification of malignant lymphomas and acute leukemias, particularly for the identification of pre-B and pre-T acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL).

    UniProt

    P04053

    途径

    DNA Damage Repair
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