IL-10 抗体
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北京 101111
Quick Overview for IL-10 抗体 (ABIN7866177)
抗原
See all IL-10 (IL10) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat anti Human IL-10
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产品特性
- IL-10 inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. It defects in IL10 are a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. Crohn disease is commonly classified as autoimmune disease.
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纯化方法
- Protein A/G Chromatography
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亚型
- IgG1
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应用备注
- Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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- IL-10 (IL10) (Interleukin 10 (IL10))
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别名
- IL-10
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背景
- Rat anti human Interleukin-4, IL-4, unconjugated
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UniProt
- P22301
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
抗原
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