UACA 抗体
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北京 101111
Quick Overview for UACA 抗体 (ABIN7865752)
抗原
See all UACA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-UACA mouse monoclonal, AE-5, purified
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纯化方法
- affinity chromatography
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免疫原
- nuclei of myeloid leukemia biopsy cells
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亚型
- IgG1 kappa
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anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 29-209) antibody
UACA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 675-725) antibodyUACA 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1-90) antibodyUACA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) antibodyUACA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1-1416) antibodyUACA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) antibodyUACA 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal AE-5 unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1309-1358) antibodyUACA 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1-50) antibodyUACA 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1075-1125) antibodyUACA 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 1-2 μg/million cells in 0,1 ml, fix cells in 4 % PFA for 10 min, at 4 °C, permeabilize with 0,2 % saponin or digitonin for 15 min, at 4 °C
WB_dilution: 1:50-1:100 (1-2 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))
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别名
- UACA
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背景
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, a mRNA differentially expressed in F9 embryonal carcinoma cells, and that is up-regulated during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway. Positive control: HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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