UACA 抗体 (AA 311-410)
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北京 101111
Quick Overview for UACA 抗体 (AA 311-410) (ABIN717191)
抗原
See all UACA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 311-410
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预测反应
- Human,Mouse,Rat,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human UACA
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Identification of UACA, EXOSC9, and ??X2 in bovine periosteal cells by mass spectrometry and immunohistochemistry." in: Analytical and bioanalytical chemistry, Vol. 406, Issue 24, pp. 5805-13, (2014) (PubMed).
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: "Identification of UACA, EXOSC9, and ??X2 in bovine periosteal cells by mass spectrometry and immunohistochemistry." in: Analytical and bioanalytical chemistry, Vol. 406, Issue 24, pp. 5805-13, (2014) (PubMed).
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- UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))
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别名
- Uaca
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背景
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Synonyms: NUCLING, Uveal autoantigen with coiled-coil domains and ankyrin repeats, UACA, KIAA1561
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
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基因ID
- 55075
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UniProt
- Q9BZF9
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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