Plasma Cell Marker 抗体
This 小鼠 单克隆 antibody specifically detects Plasma Cell Marker in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7865714
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Plasma Cell Marker 抗体 (ABIN7865714)
抗原
Plasma Cell Marker
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC)
克隆位点
EBS-O-231
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原理
- anti-Plasma-Cell-Marker mouse monoclonal, EBS-O-231, purified
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交叉反应 （详细）
- not with rat
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纯化方法
- affinity chromatography
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免疫原
- pancreatic cancer related serum mucin
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亚型
- IgG2a kappa
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anti-Plasma Cell Marker antibody
适用: 人 IHC 宿主: 小鼠 Monoclonal LIV3G11-same as 7B18 unconjugated
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应用备注
- Optional[ICC/IF_dilution]: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- Plasma Cell Marker
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别名
- Plasma-Cell-Marker
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背景
- EBS-O-231 recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm, their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Positive control: Human toncil.
抗原
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