Plasma Cell Marker 抗体
适用: 人
IHC, StM
宿主: 小鼠
Monoclonal
LIV3G11-same as 7B18
unconjugated
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- 抗原
- Plasma Cell Marker
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm, their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
- 无交叉反应
- 大鼠
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Pancreatic cancer-related mucin
- 克隆位点
- LIV3G11-same as 7B18
- 亚型
- IgG2a kappa
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anti-Plasma Cell Marker antibody
适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LIV3G11-same as 7B18 unconjugated
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- 应用备注
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Positive Control: Tonsil or lymph node.
Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 minutes at RT) [(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM PBS without BSA and without Azide.
- 储存液
- Azide free
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
- 有效期
- 24 months
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- 抗原
- Plasma Cell Marker
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