IFNA2 抗体
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北京 101111
Quick Overview for IFNA2 抗体 (ABIN7865672)
抗原
See all IFNA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Interferon α 2 mouse monoclonal, N39, purified
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纯化方法
- affinity chromatography
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免疫原
- E. coli derived recombinant human IFNalpha2c
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亚型
- IgG1 kappa
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应用备注
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WB_dilution: 1:50-1:100 (1-2 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- IFNA2 (Interferon, alpha 2 (IFNA2))
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别名
- Interferon alpha 2
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背景
- The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. N39 is specific for human IFNα2 and does not cross react with human IFNα1. N39 is directed against immunodominant epitope site I (aa112-148). Positive control: Human IFNα2, Namalwa and KGI cells. Pair: N27
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
抗原
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