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IFNA2 抗体

The 小鼠 单克隆 anti-IFNA2 antibody (Clone N27) (ABIN7865671) specifically detects IFNA2 in ELISA, WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7865671
发货至: 中国
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Quick Overview for IFNA2 抗体 (ABIN7865671)

抗原

See all IFNA2 抗体
IFNA2 (Interferon, alpha 2 (IFNA2))

适用

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宿主

  • 50
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小鼠

克隆类型

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单克隆

标记

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This IFNA2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

N27
  • 原理

    anti-Interferon α 2 mouse monoclonal, N27, purified

    纯化方法

    affinity chromatography

    免疫原

    E.coli derived recombinant human IFNalpha2c

    亚型

    IgG1 kappa
  • 应用备注

    WB_dilution: 1:50-1:100 (1-2 μg/mL)

    IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

    elisa_dilution: assay dependent

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    IFNA2 (Interferon, alpha 2 (IFNA2))

    别名

    Interferon alpha 2

    背景

    The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. N27 is specific for human IFNα2 and does not cross react with human IFNα1. N27 reacts with linear peptide 43aa-53aa, placing the epitope outside the immunodominant regions I and II. Positive control: Human IFNα2, Namalwa and KGI cells. Pair: N39

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C
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