CD74 抗体
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北京 101111
Quick Overview for CD74 抗体 (ABIN7865650)
抗原
See all CD74 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-CD74 mouse monoclonal, LN-2, purified
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交叉反应 （详细）
- negative with rat
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纯化方法
- affinity chromatography
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免疫原
- cell extracts from diffuse histiocytic lymphoma SU-DHL-4
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亚型
- IgG1 kappa
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anti-HLA-DR-gamma (CD74) (AA 1-106) antibody
CD74 适用: 人 FACS, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 2D1B3 unconjugated
anti-HLA-DR-gamma (CD74) (AA 78-222) antibodyCD74 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) (AA 64-205) antibodyCD74 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人 FACS, WB, IHC, ICC 宿主: 小鼠 Monoclonal LN2 unconjugated
anti-HLA-DR-gamma (CD74) (AA 1-106) antibodyCD74 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 2D1B11 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人 FACS, WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal PIN-1 unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人, 小鼠, Baboon FACS, WB, IHC, IF 宿主: 小鼠 Monoclonal LN-2 unconjugated
anti-HLA-DR-gamma (CD74) (AA 73-232) antibodyCD74 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-HLA-DR-gamma (CD74) antibodyCD74 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- CD74 (HLA-DR-gamma (CD74))
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别名
- CD74
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背景
- LN-2 is directed against the CD74 cluster, established during the IVth Leukocyte Typing Workshops. CD74 comprises four species of proteins (MW 41/35/33 kDa), all coded by a single gene, consisting of nine exons. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. In tissue sections anti CD74 show a binding pattern very similar to that of anti-HLA-DR. It binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. Positive control: Daudi or Raji cells. Tonsil or lymp node.
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途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
抗原
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