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hCG Holo 抗体

The 小鼠 单克隆 anti-hCG Holo antibody is suitable to detect hCG Holo in samples from 人. It has been validated for IHC.
产品编号 ABIN7865643
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for hCG Holo 抗体 (ABIN7865643)

抗原

hCG Holo

适用

宿主

  • 2
小鼠

克隆类型

  • 2
单克隆

标记

  • 2
非结合性

应用范围

  • 2
  • 1
Immunohistochemistry (IHC)

克隆位点

HCGh25
  • 原理

    anti-hCG Holo mouse monoclonal, HCGh25, purified

    纯化方法

    affinity chromatography

    免疫原

    purified hCG

    亚型

    IgG1 kappa
  • 应用备注

    IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

    IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    store at 2 - 8 °C
  • 抗原

    hCG Holo

    背景

    HCGh25 is very special because it reacts ONLY with intact-hCG and not with either free alpha- or free beta-chain of hCG. hCG is a glycoprotein composed of two non-identical, non-covalently linked polypeptide chains. The alpha subunit is identical among hCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besides trophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cell carcinoma of the lung are also positive in 90 % , 60 % and 20 % of cases respectively. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Positive control: JAR or TT Cells. Placenta.
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