CD70 抗体
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北京 101111
Quick Overview for CD70 抗体 (ABIN7865603)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-CD70 mouse monoclonal, EBS-CD-039, purified
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纯化方法
- affinity chromatography
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免疫原
- human WM-1 (Waldenstrom's macroglobulinemia) cells
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亚型
- IgG1 kappa
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应用备注
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- store at 2 - 8 °C
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
- CD70 is a 30 kDa cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and b-lymphocytes. It induces proliferation of co-stimulated T-cells, enhaces the generation of cytolytic T-cells, and constributes to T-cell activation. It futher plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. EBS-CD-039 blocks the interaction between CD27 and CD70, and has been shown to inhibit T-cell proliferation induced by dendritic cells. Positive control: Raji cells, lymph node or tonsil.
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途径
- Cancer Immune Checkpoints
抗原
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