WASP 抗体 (Tyr290)
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北京 101111
Quick Overview for WASP 抗体 (Tyr290) (ABIN7862570)
抗原
See all WASP (WAS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Tyr290
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原理
- Rabbit Anti-WASP Polyclonal Antibody
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特异性
- WASP Polyclonal Antibody detects endogenous levels of WASP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human WASP around the non-phosphorylation site of Y290
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亚型
- IgG
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 57-170) antibody
WAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7B10E4 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 39-251) antibodyWAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyVerified WAS 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 129-156), (C-Term) antibodyWAS 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyWAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 145-265) antibodyWAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 116-144) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23643 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibodyWAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 205-234) antibodyWAS 适用: 人 WB 宿主: 兔 Polyclonal RB40707 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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别名
- WASP
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背景
- WAS, IMD2, Wiskott-Aldrich syndrome protein, WASpThe Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
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分子量
- 60kD
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基因ID
- 7454
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UniProt
- P42768
抗原
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