SSTR5 抗体
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北京 101111
Quick Overview for SSTR5 抗体 (ABIN7862552)
抗原
See all SSTR5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-SSR5 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SSR5 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human SSR5 protein at AA range: 270-350
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- SSTR5 (Somatostatin Receptor 5 (SSTR5))
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别名
- SSR5
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背景
- Somatostatin receptor type 5, SS-5-R, SS5-R, SS5RSomatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by SSTR5 is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in SSTR5 results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in SSTR5.
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分子量
- 40kD
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基因ID
- 6755
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UniProt
- P35346
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途径
- Carbohydrate Homeostasis
抗原
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