ZBTB7B 抗体
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北京 101111
Quick Overview for ZBTB7B 抗体 (ABIN7863209)
抗原
See all ZBTB7B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ZBTB7B Antibody
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特异性
- TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human ZBTB7B protein
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
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别名
- ZBTB7B
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背景
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cKrox, hcKrox, T helper inducing POZ/Kruppel like factor, Th-POK, ThPOK, ZBTB15, ZBTB7B, ZFP67, Zinc finger and BTB domain containing 15, Zinc finger and BTB domain containing 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein ThPOK, ZNF857B
HeLa or HepG2 cells.
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分子量
- 58/80kDa
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基因ID
- 51043, 729279
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UniProt
- O15156
抗原
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