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VWF 抗体

The 小鼠 单克隆 anti-VWF antibody (Clone VWF-4458) (ABIN7864543) specifically detects VWF in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7864543
发货至: 中国
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Quick Overview for VWF 抗体 (ABIN7864543)

抗原

See all VWF 抗体
VWF (Von Willebrand Factor (VWF))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VWF antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

VWF-4458
  • 原理

    von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody

    特异性

    Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human VWF (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    VWF (Von Willebrand Factor (VWF))

    别名

    von Willebrand Factor

    背景

    Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

    HUVEC cells. Human tonsil.

    分子量

    250kDa

    基因ID

    7450, 440848

    UniProt

    P04275
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