Tropomyosin 抗体
Our Local Distributor
北京 101111
Quick Overview for Tropomyosin 抗体 (ABIN7864538)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Tropomyosin, alpha-1 chain (striated muscle) Antibody
-
特异性
- Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind actin filaments and function to modulate Actin-myosin interaction and stabilize actin filament structure. Tropomyosin ± is encoded by the TPM1 gene, which maps to human chromosome 15q22.2 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin b is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with actin filaments may increase the rigidity of actin filaments. Tropomyosin also interacts with caldesmon to regulate smooth muscle contraction.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant full-length TPM1 protein
-
亚型
- IgG1
-
-
anti-Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) antibody
TPM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyKD Validated TPM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2545 unconjugated Recombinant Antibody
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠, 兔, 斑马鱼, 犬, Cow, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (AA 20-69) antibodyTPM1 适用: 人, 大鼠, 小鼠, 小鸡, 兔, 斑马鱼, 犬, 豚鼠, 猴, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
-
别名
- Tropomyosin, alpha-1 chain
-
背景
-
Alpha tropomyosin, TM2, CMD1Y, Tropomyosin, skeletal muscle alpha
Human heart.
-
分子量
- 35-45kDa
-
基因ID
- 7168, 133892
-
UniProt
- P04268
-
途径
- Regulation of Actin Filament Polymerization
抗原
-
