TMPRSS2 抗体
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北京 101111
Quick Overview for TMPRSS2 抗体 (ABIN7864531)
抗原
See all TMPRSS2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TMPRSS2 (Transmembrane Serine Protease 2) Antibody
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特异性
- Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland. TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain. TMPRSS2 is expressed as a full length form and a cleaved protease domain and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human TMPRSS2 protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 140-400) antibody
TMPRSS2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 284-492) antibodyTMPRSS2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (Internal Region) antibodyVerified TMPRSS2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 383-492) antibodyTMPRSS2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 254-490) antibodyTMPRSS2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) antibodyTMPRSS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 1-30), (N-Term) antibodyTMPRSS2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18784 unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 1-492) antibodyTMPRSS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Transmembrane Protease, serine 2 (TMPRSS2) (AA 314-343) antibodyTMPRSS2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB18785 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
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别名
- TMPRSS2
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背景
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D16Ertd61e, Epitheliasin, FLJ41954, MGC6821, PP9284, PRSS10, Serine protease 10, TMPRSS2 ETV1 FUSION GENE, INCLUDED, Transmembrane protease serine 2 catalytic chain, Transmembrane protease, serine 2, EC 3.4.219
colon|Expressed strongly in small intestine. Also expressed in prostate|stomach and salivary gland.
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分子量
- 70kDa
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基因ID
- 7113, 439309
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UniProt
- O15393
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途径
- SARS-CoV-2 Protein Interactome
抗原
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