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Recombinant TSHB 抗体

The 兔 单克隆 anti-TSHB antibody (Clone TSHb-7001R) (ABIN7863474) specifically detects TSHB in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7863474
发货至: 中国
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Quick Overview for Recombinant TSHB 抗体 (ABIN7863474)

抗原

See all TSHB 抗体
TSHB (Thyroid Stimulating Hormone, beta (TSHB))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This TSHB antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

TSHb-7001R
  • 原理

    Recombinant Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker) Antibody

    特异性

    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human TSH beta fragment

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TSHB (Thyroid Stimulating Hormone, beta (TSHB))

    别名

    Thyroid Stimulating Hormone, beta

    背景

    CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB

    Normal pituitary or pituitary tumor.

    分子量

    16kDa

    基因ID

    7252, 406687

    UniProt

    P01222

    途径

    Thyroid Hormone Synthesis, Peptide Hormone Metabolism
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