TNC 抗体
Our Local Distributor
北京 101111
Quick Overview for TNC 抗体 (ABIN7864937)
抗原
See all TNC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody
-
特异性
- In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked 79oΩhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant human full-length TNC protein
-
亚型
- IgG2c, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- TNC (Tenascin C (TNC))
-
别名
- Tenascin C
-
背景
-
Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC
and lung carcinomas. Staining of normal fibroblasts serves as internal positive control (IHC).|Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast|squamous cell
-
分子量
- 210kDa and 300kDa
-
基因ID
- 3371, 143250
-
UniProt
- P24821
-
途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
抗原
-