Stathmin 1 抗体
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北京 101111
Quick Overview for Stathmin 1 抗体 (ABIN7864830)
抗原
See all Stathmin 1 (STMN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Stathmin 1 / STMN1 Antibody
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特异性
- Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human STMN1 protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Stathmin 1 (STMN1)
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别名
- Stathmin 1
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背景
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C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1
Human brain or melanoma tissue.
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分子量
- 19kDa
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基因ID
- 3925, 209983
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途径
- MAPK Pathway, Microtubule Dynamics
抗原
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