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Recombinant RPSA/Laminin Receptor 抗体

The 小鼠 单克隆 anti-RPSA/Laminin Receptor antibody is suitable to detect RPSA/Laminin Receptor in samples from 人. It has been validated for IHC.
产品编号 ABIN7863079
发货至: 中国
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Quick Overview for Recombinant RPSA/Laminin Receptor 抗体 (ABIN7863079)

抗原

See all RPSA/Laminin Receptor (RPSA) 抗体
RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

抗体类型

Recombinant Antibody

适用

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宿主

  • 73
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小鼠

克隆类型

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单克隆

标记

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This RPSA/Laminin Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

RRPSA-6333
  • 原理

    Recombinant Laminin Receptor/ RPSA (Marker of Metastatic Potential) Antibody

    特异性

    Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human RPSA protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

    别名

    Laminin Receptor

    背景

    34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA)

    colon or ovarian carcinoma., MCF-7, MDA-MB-453or HEK293 cells.Human breast

    分子量

    37-67kDa

    基因ID

    3921, 449909

    UniProt

    P08865

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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