PPARD 抗体
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北京 101111
Quick Overview for PPARD 抗体 (ABIN7861909)
抗原
See all PPARD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PPARD Antibody
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特异性
- Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that can be activated by a variety of compounds including fibratus, thiazolidinediones, prostaglandins and fatty acids. Three PPAR subtypes, designated PPARa, PPARb (also designated PPARé 79oΩ) and PPARg, have been described. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARa is abundant in primary hepatocytes, where it regulates the expression of proteins involved in fatty acid metabolism. PPARb is the most widely distributed subtype and is often expressed at high levels. PPARg is predominantly seen in adipose tissue, where it plays a critical role in regulating adipocyte differentiation. Interestingly, both the orphan nuclear hormone receptor LXRa and thyroid receptor (TR) have been shown to act as antagonists of PPARa/ RXRa binding to PPREs.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around 72-146) of human PPARD protein
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亚型
- IgG2a
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anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 1-361) antibody
PPARD 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4E3-1B11 unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 56-165) antibodyPPARD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (C-Term) antibodyVerified PPARD 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (C-Term) antibodyPPARD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 102-361) antibodyPPARD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) antibodyPPARD 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (N-Term) antibodyPPARD 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) (AA 2-100) antibodyPPARD 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) antibodyPPARD 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxisome Proliferator-Activated Receptor delta (PPARD) antibodyPPARD 适用: 人, 小鼠, 大鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 5F4 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
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别名
- PPARD
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背景
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FAAR, NR1C2, NUC1, NUCII
HeLa or MCF-7 cells.
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分子量
- 49.9kDa
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基因ID
- 5467, 696032
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UniProt
- Q03181
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
抗原
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