PAX5 抗体
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北京 101111
Quick Overview for PAX5 抗体 (ABIN7861882)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PAX5 / BSAP (Early B-Cell Marker) Antibody
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特异性
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human PAX5 protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PAX5 (Paired Box 5 (PAX5))
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别名
- PAX5
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背景
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B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5
DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen
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分子量
- 42kDa
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基因ID
- 5079, 654464
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UniProt
- Q02548
抗原
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