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NOC4L 抗体

The 小鼠 单克隆 anti-NOC4L antibody is suitable to detect NOC4L in samples from 人. It has been validated for FACS 和 IF.
产品编号 ABIN7863519
发货至: 中国
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Quick Overview for NOC4L 抗体 (ABIN7863519)

抗原

NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NOC4L antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

PCRP-NOC4L-1B2
  • 原理

    Nucleolar complex-associated protein 4-like protein (NOC4L) Antibody

    特异性

    Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human NOC4L protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

    别名

    Nucleolar complex-associated protein 4-like protein

    背景

    NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein

    HeLa or 293T cells.

    分子量

    58.4kDa

    基因ID

    79050, 558536

    UniProt

    Q9BVI4
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