NEUROD2 抗体
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Quick Overview for NEUROD2 抗体 (ABIN7863188)
抗原
See all NEUROD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NEUROD2 (Neurogenic Differentiation 2) (Transcription Factor) Antibody
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特异性
- Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D ( æ2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human NEUROD2 protein
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亚型
- IgG2b, kappa
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anti-Neurogenic Differentiation 2 (NEUROD2) (Internal Region) antibody
NEUROD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 266-375) antibodyNEUROD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 1-382) antibodyNEUROD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 71-120) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (AA 1-382) antibodyNEUROD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (Internal Region) antibodyNEUROD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (C-Term) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurogenic Differentiation 2 (NEUROD2) (Center) antibodyNEUROD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
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别名
- NEUROD2
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背景
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bHLHa1, class A basic helix loop helix protein 1, NDR2, NDRF, NeuroD-related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic differentiation 2, Neurogenic differentiation factor 2, neuronal differentiation 2
HeLa cells. Human brain.
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分子量
- ~41kDa
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基因ID
- 4761, 322431
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UniProt
- Q15784
抗原
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