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NEUROD2 抗体 (Internal Region)

NEUROD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263551
发货至: 中国
  • 抗原 See all NEUROD2 抗体
    NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
    抗原表位
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 48
    • 20
    • 19
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 42
    • 3
    • 3
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEUROD2 antibody is un-conjugated
    应用范围
    • 34
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    NDF2 Antibody detects endogenous levels of total NDF2.
    预测反应
    Pig,Bovine,Horse,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NDF2, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
    别名
    NEUROD2 (NEUROD2 产品)
    别名
    NEUROD2 antibody, ndrf antibody, MGC145932 antibody, Ndrf antibody, bHLHa1 antibody, ndr2 antibody, wu:fj49a11 antibody, zNdr2 antibody, NDRF antibody, neuronal differentiation 2 antibody, neurogenic differentiation 2 antibody, NEUROD2 antibody, neurod2 antibody, Neurod2 antibody
    背景

    Description: Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation, prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections, involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).

    Gene: NEUROD2

    分子量
    48kDa
    基因ID
    4761
    UniProt
    Q15784
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