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MEF2D 抗体

The 小鼠 单克隆 anti-MEF2D antibody (Clone PCRP-MEF2D-3A4) (ABIN7863121) specifically detects MEF2D in IHC, FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7863121
发货至: 中国
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Quick Overview for MEF2D 抗体 (ABIN7863121)

抗原

See all MEF2D 抗体
MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MEF2D antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

PCRP-MEF2D-3A4
  • 原理

    MEF2D / Myocyte enhancer factor 2D (Transcription Factor) Antibody

    特异性

    The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5 and MRF4, are one class of identified factors. A second family of DNA-binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human MEF2D protein

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

    别名

    MEF2D

    背景

    MADS box transcription factor 2 polypeptide D, Myocyte specific enhancer factor 2, polypeptide D

    HeLa cells.

    分子量

    55.94kDa

    基因ID

    4209, 314327

    UniProt

    Q14814
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