IFNA 抗体
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北京 101111
Quick Overview for IFNA 抗体 (ABIN7862971)
抗原
See all IFNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Interferon alpha Antibody
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特异性
- This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Produced by macrophages, IFN-alphas have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human IFNA1 protein
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亚型
- IgG1, kappa
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anti-Interferon alpha (IFNA) antibody
IFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 28-227) antibodyIFNA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-192) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 1-187) antibodyIFNA 适用: 豚鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-189) antibodyIFNA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 23-187) antibodyIFNA 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-172) antibodyIFNA 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 猕猴 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IFNA (Interferon alpha (IFNA))
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别名
- Interferon alpha
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背景
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IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D
Stimulated human peripheral blood mononuclear cells
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分子量
- 16-27kDa
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基因ID
- 3439
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UniProt
- P01562
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途径
- JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
抗原
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