IgD 抗体
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北京 101111
Quick Overview for IgD 抗体 (ABIN7861494)
抗原
See all IgD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker) Antibody
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特异性
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with t heavy chains and either é 79oΩ or é 79oΩ light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Full-length human IGHD protein
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亚型
- IgG2a, kappa
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anti-IgD antibody
适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-IgD (AA 1-240) antibody适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody适用: 人 IHC 宿主: 兔 Monoclonal 701R unconjugated Recombinant Antibody
anti-IgD (AA 1-576) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IgD antibody适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal IgD26 unconjugated
anti-IgD antibody (FITC)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 FITC
anti-IgD antibody (iFluor™700)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™700
anti-IgD antibody (iFluor™647)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™647
anti-IgD antibody (mFluor™450)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 mFluor™450
anti-IgD antibody适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- IgD
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别名
- IGHD
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背景
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Ig delta chain C region, IGHD, Immunoglobulin heavy constant delta
Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues
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分子量
- 44-80kDa (heavy chain), 21-25kDa (kappa light chain)
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基因ID
- 3495, 510635
抗原
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