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IgD 抗体

适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal IgD26 unconjugated
产品编号 ABIN6939707
发货至: 中国
  • 抗原 See all IgD 抗体
    IgD
    适用
    • 43
    • 10
    宿主
    • 26
    • 17
    • 9
    小鼠
    克隆类型
    • 29
    • 23
    单克隆
    标记
    • 14
    • 6
    • 4
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This IgD antibody is un-conjugated
    应用范围
    • 22
    • 19
    • 13
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Full-length human IGHD protein
    克隆位点
    IgD26
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IgD Primary Antibody
  • 应用备注

    Positive Control: Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    IgD
    别名
    IGHD (IgD 产品)
    别名
    IgD antibody, Igh-5 antibody, immunoglobulin heavy constant delta antibody, immunoglobulin delta heavy chain constant region antibody, Ighd antibody, Igd antibody, IGHD antibody
    物质类
    Antibody
    背景
    Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
    分子量
    44-80kDa (heavy chain), 21-25kDa (kappa light chain)
    基因ID
    3495
    UniProt
    P01880
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