HDAC7 抗体
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北京 101111
Quick Overview for HDAC7 抗体 (ABIN7861450)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HDAC7 Antibody
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特异性
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. Mammalian HDAC7 is a histone deacetylase that interacts with the adaptor mSin3A. The interaction of HDAC7 with mSin3A suggests the association of multiple repression complexes of transcription factors.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human HDAC7 protein
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亚型
- IgG
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anti-Histone Deacetylase 7 (HDAC7) (AA 1-276) antibody
HDAC7 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2B11-1C1 unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 902-952) antibodyHDAC7 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (C-Term) antibodyHDAC7 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 400-500) antibodyHDAC7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 1-276) antibodyHDAC7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (Internal Region) antibodyHDAC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (Tyr721) antibodyHDAC7 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 902-952) antibodyHDAC7 适用: 人 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 7 (HDAC7) (AA 846-875), (C-Term) antibodyHDAC7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33269 unconjugated
anti-Histone Deacetylase 7 (HDAC7) antibodyHDAC7 适用: 人 WB 宿主: 兔 Monoclonal 3H7 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7
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背景
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DKFZP586J0917, HDAC7A
HeLa cells.
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分子量
- 105kDa
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基因ID
- 51564, 200063
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UniProt
- Q8WUI4
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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