HDAC7 抗体 (N-Term)
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北京 101111
Quick Overview for HDAC7 抗体 (N-Term) (ABIN5557306)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- HDAC7 Recombinant Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human HDAC7 protein, around N-terminal 150aa.
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亚型
- IgG
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应用备注
- WB(1:500-2000), IHC-P(1:50-200), IHC-F(1:50-200), IF(1:50-200), Flow-Cyt(1:50-200), ICC/IF(1:50-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7
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背景
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Synonyms: Histone deacetylase 7, HDAC7
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
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基因ID
- 51564
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UniProt
- Q8WUI4
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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