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HDAC7 抗体 (N-Term)

The 兔 单克隆 anti-HDAC7 antibody is suitable to detect HDAC7 in samples from 人. It has been validated for WB, IHC (p), IF, FACS, ICC 和 IHC (fro).
产品编号 ABIN5557306
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC7 抗体 (N-Term) (ABIN5557306)

抗原

See all HDAC7 抗体
HDAC7 (Histone Deacetylase 7 (HDAC7))

适用

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宿主

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克隆类型

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单克隆

标记

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This HDAC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

3H7
  • 抗原表位

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    N-Term

    原理

    HDAC7 Recombinant Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human HDAC7 protein, around N-terminal 150aa.

    亚型

    IgG
  • 应用备注

    WB(1:500-2000), IHC-P(1:50-200), IHC-F(1:50-200), IF(1:50-200), Flow-Cyt(1:50-200), ICC/IF(1:50-100)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    HDAC7 (Histone Deacetylase 7 (HDAC7))

    别名

    HDAC7

    背景

    Synonyms: Histone deacetylase 7, HDAC7

    Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

    基因ID

    51564

    UniProt

    Q8WUI4

    途径

    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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