HDAC1 抗体
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北京 101111
Quick Overview for HDAC1 抗体 (ABIN7863567)
抗原
See all HDAC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Histone Deacetylase 1 (HDAC3) Antibody
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特异性
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human HDAC3 protein
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亚型
- IgG2b
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anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IF, ICC, IP, IHC (p), ChIP, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal E22 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibodyHDAC1 适用: 人 IHC, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) antibodyKO Validated HDAC1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 450-482) antibodyHDAC1 适用: 人 WB, IHC, ELISA, IF, FM, MA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibodyVerified HDAC1 适用: 人, 小鼠 WB, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Histone Deacetylase 1 (HDAC1) (AA 449-482), (C-Term) antibodyHDAC1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB5642 unconjugated
anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibodyHDAC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 斑马鱼, 豚鼠, 马, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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别名
- Histone Deacetylase 1
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背景
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HD3, HDAC 3, HDAC3, HDAC3_HUMAN, Histone deacetylase 3, RPD3 2, RPD3, RPD3-2, SMAP45
HeLa or Jurkat cells.
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分子量
- 49kDa
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基因ID
- 8841, 519632
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UniProt
- O15379
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途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
抗原
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