GPI 抗体
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Quick Overview for GPI 抗体 (ABIN7861358)
抗原
See all GPI 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Glucose 6-Phosphate Isomerase Antibody
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特异性
- Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human full-length GPI protein
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亚型
- IgG2b, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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别名
- Glucose 6-Phosphate Isomerase
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背景
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AMF, aurocrine motility factor, EC 5.2.1.9, GNPI, Gpi1, hexose monophosphate isomerase, neuroleukin, NLK, oxoisomerase, PGI, PHI, phosphoglucose isomerase, phosphosaccharomutase, SA-36, sperm antigen 36
PC3, T47D, HepG2, MCF-7 or A549 cells. Human kidney, brain, pancreas or thyroid carcinoma.
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分子量
- 55kDa
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基因ID
- 2821, 466471
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UniProt
- P06744
抗原
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