GLIS3 抗体
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北京 101111
Quick Overview for GLIS3 抗体 (ABIN7862708)
抗原
See all GLIS3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GLIS family zinc finger 3 (GLIS3) / ZNF515 Antibody
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特异性
- GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human GLIS3 protein
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))
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别名
- GLIS family zinc finger 3
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背景
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FLJ38999, FLJ90578, GLI similar 3, GLI SIMILAR PROTEIN 3, GLIS family zinc finger 3, MGC33662, OK/KNS-cl.4, Zinc finger protein 515, Zinc finger protein GLIS3, ZNF515
A549 or U-2 OS cells.
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分子量
- 84kDa
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基因ID
- 169792, 162125
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UniProt
- Q8NEA6
抗原
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