EIF4E 抗体
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北京 101111
Quick Overview for EIF4E 抗体 (ABIN7862735)
抗原
See all EIF4E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- EIF4E Antibody
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特异性
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4E, eIF4A and eIF4G. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA cap during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E, eIF4A and the eIF3 complex.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human EIF4E protein
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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别名
- EIF4E
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背景
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AUTS19, CBP, eIF-4F 25 kDa subunit, eIF4E, EIF4E1, EIF4EL1, EIF4F, Eukaryotic translation initiation factor 4E like 1, Messanger RNA (mRNA) Cap Binding Protein eIF 4E
HeLa, Raji or U87 cells.
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分子量
- 25.1kDa
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基因ID
- 1977, 249718
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UniProt
- P06730
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途径
- BCR Signaling
抗原
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