CHID1 抗体
Our Local Distributor
北京 101111
Quick Overview for CHID1 抗体 (ABIN7861113)
抗原
See all CHID1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- SI-CLP / Chitinase Domain Containing 1 (CHID1) Antibody
-
特异性
- SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.
-
纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
免疫原
- Recombinant full-length human CHID1 protein
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Prepared in 10 mM PBS
-
储存液
- Azide free
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- CHID1 (Chitinase Domain Containing 1 (CHID1))
-
别名
- SI-CLP
-
背景
-
CHID1, Chitinase domain containing 1, FLJ42707, GL008, MGC3234, PSEC0104, SB139, SI-CLP, SICLP, Stabilin 1 interacting chitinase like protein
colon|HeLa cells. Human fetal gut|liver or heart.
-
分子量
- 42-48kDa
-
基因ID
- 66005, 144468
-
UniProt
- Q9BWS9
抗原
-