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CHID1 抗体

This 小鼠 单克隆 antibody specifically detects CHID1 in IHC. It exhibits reactivity toward 人.
产品编号 ABIN7863924
发货至: 中国
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Quick Overview for CHID1 抗体 (ABIN7863924)

抗原

See all CHID1 抗体
CHID1 (Chitinase Domain Containing 1 (CHID1))

适用

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  • 5
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  • 1

宿主

  • 21
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  • 1
小鼠

克隆类型

  • 21
  • 4
单克隆

标记

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This CHID1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

CHID1-6368
  • 原理

    SI-CLP / Chitinase Domain Containing 1 (CHID1) Antibody

    特异性

    SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant full-length human CHID1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    CHID1 (Chitinase Domain Containing 1 (CHID1))

    别名

    SI-CLP

    背景

    CHID1, Chitinase domain containing 1, FLJ42707, GL008, MGC3234, PSEC0104, SB139, SI-CLP, SICLP, Stabilin 1 interacting chitinase like protein

    colon|HeLa cells. Human fetal gut|liver or heart.

    分子量

    42-48kDa

    基因ID

    66005, 144468

    UniProt

    Q9BWS9
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