Recombinant CD5 抗体
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北京 101111
Quick Overview for Recombinant CD5 抗体 (ABIN7863591)
抗原
See all CD5 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD5 (Mantle Cell Lymphoma Marker) Antibody
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特异性
- The CD5 antigen is a transmembrane glycoprotein expressed on the surface of practically all mature human T-cells (about 10 % of CD4+ T-cells being CD5 negative). In immature (CD34+) T-cells, CD5 is weakly expressed, the intensity of expression increasing with maturation. CD5 is also expressed in a small subset of normal human B-cells (20 % of B-cells in the peripheral blood, scattered cells in the lymph node mantle zone). The CD5+ cells are probably involved in B-T interaction and their ligand is CD72 which is expressed on all B cells. It appears that CD5+ B-cells on activation primarily produce IgM. They also produce more autoantibodies than normal CD5 negative B-cells. Thus, the CD5+ B-cell population is expanded in rheumatoid arthritis and systemic lupus erythematosus. The CD5 antibody reacts with CD5 expressed on B and T cells, and may be a useful aid for the classification of B and T-cell malignancies. This includes B-cell chronic lymphoid leukemia (B-CLL), B-cell small lymphocytic lymphoma (B-SLL), mantle cell lymphoma (MCL) and T-cell lymphoma and leukemia.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length protein corresponding to human CD5
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亚型
- IgG, kappa
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anti-CD5 (CD5) (AA 269-366) antibody
CD5 适用: 人 FACS, WB, IHC, IF 宿主: 小鼠 Monoclonal CD5-2416 unconjugated
anti-CD5 (CD5) (AA 105-210) antibodyCD5 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-CD5 (CD5) (AA 25-372) antibodyCD5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD5 (CD5) (AA 269-366) antibodyCD5 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal CD5-2418 unconjugated
anti-CD5 (CD5) (AA 27-233) antibodyCD5 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6A11 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人, 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6C3B2 unconjugated
anti-CD5 (CD5) antibodyCD5 适用: 人 FACS, WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal L17F12 unconjugated
anti-CD5 (CD5) (AA 403-495) antibodyCD5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-CD5 (CD5) (AA 25-371) antibodyCD5 适用: 人 WB, IHC, ICC 宿主: 兔 Monoclonal BLR218K unconjugated Recombinant Antibody
anti-CD5 (CD5) (AA 25-372) antibodyCD5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3D3G6 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD5
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别名
- CD5
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背景
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CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5
293T, Ramos or MOLT-4 cells. Human tonsil or lymph node.
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分子量
- ~67kDa
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基因ID
- 921, 58685
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UniProt
- P06127
抗原
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