Recombinant CTNND1 抗体 (AA 868-968)
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Quick Overview for Recombinant CTNND1 抗体 (AA 868-968) (ABIN7862681)
抗原
See all CTNND1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 868-968
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原理
- Recombinant p120 / Catenin, delta-1 (CTNND1) Antibody
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特异性
- Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, p120 catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins. p120 is a proliferation-associated nucleolar protein found in most human malignant tumors, but not in resting normal cells. In colorectal cancer the altered localization of p120 catenin corresponds with loss of cytoplasmic localization of E-cadherin. Studies have shown accurate categorization of ductal vs. lobular neoplasia in the breast was achieved with p120 staining. p120 expression further clarifies the separation of low-grade ductal carcinoma in situ from lobular neoplasia. Studies also have shown that altered expression of p120 catenin antibody predicts poor outcome in invasive breast cancer.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa868-968) of human p120 (exact sequence is proprietary)
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亚型
- IgG1, kappa
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anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibody
CTNND1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 573-832) antibodyCTNND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyKD Validated CTNND1 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB3025 unconjugated Recombinant Antibody
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyKD Validated CTNND1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB5775 unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 64-930) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 64-930) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 8G7E4 unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (Tyr228) antibodyCTNND1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 482-605) antibodyCTNND1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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别名
- p120
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背景
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Cadherin-associated Src substrate (CAS), Catenin (cadherin associated protein) delta 1, Catenin delta-1, CTNND1, p120 catenin, P120 CTN, p120(cas), p120(ctn), P120CAS, P120CTN
Human colon tissue.
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分子量
- 120kDa
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基因ID
- 1500, 166011
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UniProt
- O60716
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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