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APOA1 抗体 (AA 83-167)

The 小鼠 单克隆 anti-APOA1 antibody is suitable to detect APOA1 in samples from 人. It has been validated for IHC.
产品编号 ABIN7862959
发货至: 中国
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Quick Overview for APOA1 抗体 (AA 83-167) (ABIN7862959)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This APOA1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

APOA1-3661
  • 抗原表位

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    AA 83-167

    原理

    Apolipoprotein A1 / APOA1 Antibody

    特异性

    Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Human recombinant APOA1 protein fragment (around aa 83-167) (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    Apolipoprotein A1

    背景

    ApoA1, Brp14, high density lipoprotein uptake, Ltw1, Lvtw1, Sep1, Sep2

    Human liver.

    分子量

    28kDa

    基因ID

    335, 93194

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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