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Recombinant CD7 抗体 (AA 72-175)

The 兔 单克隆 anti-CD7 antibody is suitable to detect CD7 in samples from 人. It has been validated for WB 和 IHC.
产品编号 ABIN7863599
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD7 抗体 (AA 72-175) (ABIN7863599)

抗原

See all CD7 抗体
CD7

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CD7-6388R
  • 抗原表位

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    AA 72-175

    原理

    Recombinant CD7 (T-Cell Leukemia Marker) Antibody

    特异性

    Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa 72-175) of human CD7 protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD7

    别名

    CD7

    背景

    GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

    HePG-2 or Jurkat cells. Human lymph node or tonsil.

    分子量

    40kDa

    基因ID

    924, 186820

    UniProt

    P09564

    途径

    Cell-Cell Junction Organization
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