电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant RRM1 抗体 (AA 700-800)

This 兔 单克隆 antibody specifically detects RRM1 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7863356
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant RRM1 抗体 (AA 700-800) (ABIN7863356)

抗原

See all RRM1 抗体
RRM1 (Ribonucleotide Reductase M1 (RRM1))

抗体类型

Recombinant Antibody

适用

  • 101
  • 43
  • 31
  • 10
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 98
  • 8

克隆类型

  • 73
  • 33
单克隆

标记

  • 52
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RRM1 antibody is un-conjugated

应用范围

  • 63
  • 29
  • 25
  • 22
  • 15
  • 13
  • 13
  • 9
  • 8
  • 8
  • 4
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

RRM1-4372R
  • 抗原表位

    • 15
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-800

    原理

    Recombinant Ribonucleotide Reductase M1 / RRM1 Antibody

    特异性

    Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    RRM1 (Ribonucleotide Reductase M1 (RRM1))

    别名

    Ribonucleotide Reductase M1

    背景

    Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, RR1, RRM1, RIR1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit

    Human breast, lung or colon carcinoma tissue. Human Intestine, Human Skin, A549, HEK293 or K-562

    分子量

    94kDa

    基因ID

    6240, 445705

    途径

    Positive Regulation of Endopeptidase Activity
You are here: