Recombinant RRM1 抗体 (AA 700-800)
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Quick Overview for Recombinant RRM1 抗体 (AA 700-800) (ABIN7863356)
抗原
See all RRM1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-800
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原理
- Recombinant Ribonucleotide Reductase M1 / RRM1 Antibody
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特异性
- Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)
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亚型
- IgG, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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别名
- Ribonucleotide Reductase M1
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背景
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Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, RR1, RRM1, RIR1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit
Human breast, lung or colon carcinoma tissue. Human Intestine, Human Skin, A549, HEK293 or K-562
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分子量
- 94kDa
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基因ID
- 6240, 445705
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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