TEK 抗体 (AA 700-1000)
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Quick Overview for TEK 抗体 (AA 700-1000) (ABIN7860589)
抗原
See all TEK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-1000
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原理
- CD202b / TIE2 / TEK (Tyrosine Kinase with Ig and EGF Homology Domains 2) Antibody
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特异性
- This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa700-1000) of human TEK protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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别名
- CD202b
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背景
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TIE2, VMCM, GLC3E, TIE-2, VMCM1, CD202B
Human lung, placenta or spleen.
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分子量
- 65kDa
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基因ID
- 7010
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UniProt
- Q02763
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途径
- RTK signaling, Growth Factor Binding
抗原
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