FGF2 抗体 (AA 7-96)
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Quick Overview for FGF2 抗体 (AA 7-96) (ABIN7860583)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 7-96
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原理
- bFGF / FGF2 Antibody
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特异性
- Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 7-96) of human FGF2 protein (exact sequence is proprietary)
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亚型
- IgG2, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- bFGF
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背景
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Basic fibroblast growth factor bFGF, BFGF, Fgf2, FGF2 basic, FGFB, Fibroblast growth factor, basic, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, Prostatropin
Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.
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分子量
- 18/21/24kDa
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基因ID
- 2247, 65425
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UniProt
- P09038
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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