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APOB 抗体 (AA 592-689)

The 小鼠 单克隆 anti-APOB antibody (Clone APOB-4335) (ABIN7862964) specifically detects APOB in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7862964
发货至: 中国
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Quick Overview for APOB 抗体 (AA 592-689) (ABIN7862964)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 124
  • 26
  • 25
  • 6
  • 2

宿主

  • 80
  • 56
  • 14
  • 2
  • 1
小鼠

克隆类型

  • 82
  • 70
单克隆

标记

  • 70
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This APOB antibody is un-conjugated

应用范围

  • 87
  • 51
  • 42
  • 31
  • 31
  • 20
  • 16
  • 9
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  • 2
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Immunohistochemistry (IHC)

克隆位点

APOB-4335
  • 抗原表位

    • 13
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    AA 592-689

    原理

    Apolipoprotein B / APOB Antibody

    特异性

    Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Human recombinant APOB protein fragment (around aa 592-689) (exact sequence is proprietary)

    亚型

    IgG2b, IgG2c, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    Apolipoprotein B

    背景

    ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4

    Human liver or kidney tissue.

    分子量

    512kDa

    基因ID

    338, 120759

    UniProt

    P04114

    途径

    Lipid Metabolism
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