APOB 抗体 (AA 592-689)
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北京 101111
Quick Overview for APOB 抗体 (AA 592-689) (ABIN7862964)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 592-689
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原理
- Apolipoprotein B / APOB Antibody
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特异性
- Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Human recombinant APOB protein fragment (around aa 592-689) (exact sequence is proprietary)
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亚型
- IgG2b, IgG2c, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- APOB (Apolipoprotein B (APOB))
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别名
- Apolipoprotein B
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背景
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ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4
Human liver or kidney tissue.
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分子量
- 512kDa
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基因ID
- 338, 120759
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UniProt
- P04114
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途径
- Lipid Metabolism
抗原
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