TdT 抗体 (AA 52-192)
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Quick Overview for TdT 抗体 (AA 52-192) (ABIN7862714)
抗原
See all TdT (DNTT) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 52-192
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原理
- TdT / DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Antibody
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特异性
- Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3'-hydroxyl end of DNA primers without template direction. The enzyme thus provides a unique method for the labeling of the 3' termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 52-192) of human DNTT protein (exact sequence is proprietary)
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
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别名
- TdT
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背景
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Deoxynucleotidyltransferase terminal, DNA Nucleotidylexotransferase, DNTT, Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase, Terminal transferase
Human thymus. Jurkatcells.
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分子量
- 58kDa
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基因ID
- 1791, 534206
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UniProt
- P04053
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途径
- DNA Damage Repair
抗原
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